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We stand at the frontiers of chemistry and biology, developing small molecules as chemical tools to understand and modulate complex biological systems. We utilize synthetic chemistry, biochemistry, and state-of-the art mass spectrometry to elucidate the structure, dynamics, and reactivity of poorly characterized, previously "undruggable" members of the proteome with pathological implications (e.g. cancer, diabetes, infectious diseases). 

Latest Lab News 
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Check out this exciting article on Cell Chemical Biology with the Bogyo Lab! Congrats to Daniel (and all authors)!

September 19, 2024

 

An amazing study on mixed alkyl/aryl phosphonates as identifiers of metabolic serine hydrolases by John and Matt! Great to be a part of this collaboration!

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Congrats, Brittney, Dany, Daniel (and all authors) on publishing this impressive article in ChemRxiv!

August 13, 2024

 

Our recent discovery of a first-in-class acrylamide- and VHL-based PROTAC for metallothionein 2A (MT2A) is now online in ChemRxiv Biological and Medicinal Chemistry!

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Congrats, Nan, Dany and Daniel on publishing this interesting article in ACS Chemical Research in Toxicology!

March 14, 2024

 

Check out the stunning quantitative chemical proteomics platform that globally profiles the reactivities of proteinaceous cysteines upon cellular zinc depletion with this article!

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Lab Culture

We strive to make our lab a family by cultivating a fun yet hardworking lab environment. We regularly partake in lab events, such lab dinners and team-building activities.

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